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Articles
PUBLICATIONS
Articles (prior to independent career)
Au-Catalyzed Intramolecular Hydroalkoxylation of gem-Difluorinated Alkynols
Hamel, J.-D.; Paquin, J.-F. J. Fluorine Chem. 2018, 216, 11-23.
13.
Activation of C–F Bonds α to C–C Multiple Bonds
Hamel, J.-D.; Paquin, J.-F. Chem. Commun. 2018, 54, 10224-10239.
12.
Synthesis of Monofluoroalkenes: A Leap Forward
Drouin, M.; Hamel, J.-D.; Paquin, J.-F. Synthesis 2018, 50, 881-955.
11.
Hydrogen-Bond-Promoted Friedel-Crafts Reaction of Secondary Propargylic Fluorides: Preparation of 1-Alkyl-1-aryl-2-alkynes
​Hamel, J.-D.; Beaudoin, M.; Cloutier, M.; Paquin, J.-F. Synlett 2017, 2823-2828.
10.
Highly Regioselective Gold-Catalyzed Formal Hydration of Propargylic gem-Difluorides: Synthetic Equivalent to the Selective Deoxofluorination of 1,3-Diketones
​Hamel, J.-D.; Hayashi, T.; Cloutier, M.; Savoie, P. R.; Thibeault, O.; Beaudoin, M.; Paquin, J.-F. Org. Biomol. Chem. 2017, 15, 9830-9836.
9.
Exploiting a Difference in Leaving Group Ability: An Approach to β-Substituted Monofluoroalkenes Using gem-Chlorofluoropropenes
​Hamel, J.-D.; Cloutier, M.; Paquin, J.-F. Org. Lett. 2016, 18, 1852-1855.
8.
Exploiting 3,3-Difluoropropenes for the Synthesis of Monofluoroalkenes
​Drouin, M.; Hamel, J.-D.; Paquin, J.-F. Synlett 2016, 27, 821-830.
7.
Monofluorination of Organic Compounds: 10 Years of Innovation
Champagne, P. A.; Desroches, J.; Hamel, J.-D.; Vandamme, M.; Paquin J.-F. Chem. Rev. 2015, 115, 9073-9174.
6.
Synthesis of Monofluoroalkenes using a Pt-Catalyzed Amination Reaction of Cyclic 3,3-Difluoropropenes with Secondary Aliphatic Amines
Hamel, J.-D.; Drouin, M.; Paquin, J.-F. J. Fluorine Chem. 2015, 174, 81-87.
5.
TaMe₃Cl₂-Catalyzed Intermolecular Hydroaminoalkylation: A Simple Complex for Enhanced Reactivity and Expanded Substrate Scope
Zhang, Z.; Hamel, J.-D.; Schafer, L. L. Chem. Eur. J. 2013, 19, 8751-8754.
4.
Halogenation of Primary Alcohols Using a Tetraethylammonium Halide/[Etâ‚‚NSFâ‚‚]BFâ‚„
Combination
​Pouliot, M.-F.; Mahé, O.; Hamel, J.-D.; Desroches, J.; Paquin, J.-F. Org. Lett. 2012, 14, 5428-5431.
3.
Synthesis of 2-Oxazolines and Related N-Containing Heterocycles Using [Etâ‚‚NSFâ‚‚]BFâ‚„ as a Cyclodehydration Agent
​Pouliot, M.-F.; Angers, L.; Hamel, J.-D.; Paquin, J.-F. Tetrahedron Lett. 2012, 53, 4121-4123.
2.
Synthesis of 1,3,4-Oxadiazoles from 1,2-Diacylhydrazines Using [Etâ‚‚NSFâ‚‚]BFâ‚„ as a Practical Cyclodehydration Agent
Pouliot, M.-F.; Angers, L.; Hamel, J.-D.; Paquin, J.-F. Org. Biomol. Chem. 2012, 10, 988-993.
1.
Book chapters (prior to independent career)
Hamel, J.-D.; Paquin, J.-F. “Propargylic Fluorides (Update 2016)” In Science of Synthesis Knowledge Updates 2016/1; Bagley, M. C., Paquin, J.-F., Eds.; Georg Thieme Verlag KG: Stuttgart-New York, 2016; chapter 34.5.2, pp. 409-418.
1.
Book chapters
Semeniuk, T.; Hamel, J.-D. “Exploiting C–F bond activation for the synthesis of organofluorine compounds” In Modern Strategies in Organofluorine Chemistry; Paquin, J.-F., Ed.; upcoming.
2.
Hamel, J.-D.; Ferlet, R.; Chabaud, L.; Paquin, J.-F. “C–F Activation with Metal and Organocatalysts” In PATAI’s Chemistry of Functional Groups; Rappoport, Z., Ed.; pp. 1-55.
1.
Chemoselective Divergence via Substrate Control: Decarboxylative and Decarbonylative Coupling of 2-Oxoacids with Allylic Difluorides
Semeniuk, T.; Toporkov, D.; Pounder, A.; Wetmore, S. D.; Hamel, J.-D. Eur. J. Org. Chem. 2025, e202501058.
5.
N-(2-Fluoro-2-propen-1-yl)-5-(trifluoromethyl)-2-pyridinecarboxamide
Semeniuk, T.; Hamel, J.-D. Molbank 2025, 2025, M2078.
4.
3-((Benzyloxy)carbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid
Toporkov, D. D.; Nelson, S. K.; Hamel, J.-D.; Boeré, R. T. Molbank 2025, 2025, M2075.
3.
Photoredox Decarboxylative 3-Fluoroallylation of α-Amino Acids
Semeniuk, T.; Challenger, J.; Dudas, T.; Toporkov, D.; van Hoeve, M. D.; Hamel, J.-D. Eur. J. Org. Chem. 2025, 28, e202500519.
2.
Photocatalytic Defluorinative α-Aminoalkylation of Allylic Difluorides
Semeniuk, T.; Dudas, T.; Okeh, E.; Felesky, T.; Hamel, J.-D. J. Org. Chem. 2024, 89, 13669-13677.
1.
Decarboxylative Redox Bicyclo[1.1.1]pentylation: Benchmarking the Influence of Backbone Substituents on C–C Bond-Forming Reactions
Nelson, S. K.; Pounder, A.; Thwaites, A. E.; Wetmore, S. D.; Hamel, J.-D. Org. Lett. 2025, ASAP.
6.
Research Group in Organofluorine Chemistry and Catalysis
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